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KMID : 0942820020010020134
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Journal of Korean Brain Tumor Society
2002 Volume.1 No. 2 p.134 ~ p.141
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Clinical Analysis of Choroid Plexus Tumors
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Kim Jae-Myeong
Ra Young-Shin
Ahn Young-Sang
Ghim Thad T.
Kwun Byung-Duk
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Abstract
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Clinical features, surgical management and prognosis of choroid plexus neoplasms depend on various factors including age of onset, location of tumor, histologic findings and presence of hydrocephalus. Nine patients with choroid plexus papilloma(CPP) and 2 with choroid plexus carcinoma(CPC) were analyzed regarding clinical features, radiologic findings, surgical methods, postoperative complications and outcomes retrospectively. Tumor locations were lateral ventricle (6 patients), 4th ventricle(3) and multiple(2). The most frequent symptoms and signs were macrocephaly, ataxic gait, and hemiparesis. Surgical approaches were transcortical posterior parietal approach(7 patients) transcallosal approach (1), suboccipital midline craniotomy(3), and orbitofrontal approach(1). Among 9 CPPs, total resection of tumor was performed in 7 patients who have been in complete remission. Two patients with subtotal resection of CPP underwent radiosurgery for residual tumors subsequently. One was stable but the other was dead 11 months later because of brain stem edema. Two patients with CPC underwent subtotal tumor resection, adjuvant chemotherapy and/or radiosurgery. One has been in complete remission and the other was dead because of hypernatremia during chemotherapy. Among 9 patients with preoperative hydrocephalus, 7 patients improved without shunting procedure but 2 needed shunt surgery eventually. Conclusively, Complete resection of tumor is the important prognostic factor in choroid plexus tumors and postoperative adjuvant therapy is helpful to manage CPCs. Also hydrocephalus of most patients can be managed by successful removal of tumors without shunt.
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KEYWORD
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Choroid plexus neoplasms, Surgery, Chemotherapy, Outcome, Hydrocephalus
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